MyoKardia to Evaluate Mavacamten as an Alternative to Septal Reduction Therapy in Obstructive Hypertrophic Cardiomyopathy Patients

MyoKardia to Evaluate Mavacamten as an Alternative to Septal Reduction Therapy in Obstructive Hypertrophic Cardiomyopathy Patients

Planned Study Will Assess Effect Mavacamten on the Need SRT MyoKardia to Evaluate Among HCM Patients Invasive Procedures SOUTH SAN Sept. 10, Inc. (Nasdaq: MYOK), with support the established referral networks those centers. The obstructive HCM patients referred SRT, D. , D. , Clinical Operations, serving as Principal Investigator.

Data Support Progression to Phase 2 Clinical Trial in Patients with Obstructive Hypertrophic Cardiomyopathy to Begin in Q4 2019 SOUTH SAN FRANCISCO, Calif. , Sept. 16, 2019 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (CYTK) today announced data from the Phase 1 study of CK-3773274 (CK-274) were presented in a poster session at the HFSA 23rd Annual Scientific Meeting in Philadelphia. The study met its primary and secondary objectives to assess the safety and tolerability of single and multiple oral doses obstructive cardiomyopathy of CK-274, describe the pharmacokinetics (PK) of CK-274 and its pharmacodynamic effects (PD) as measured by echocardiography, as well as to characterize the PK/PD relationship with regards to cardiac function. These data support the advancement of CK-274 into a Phase 2 clinical trial in patients with obstructive hypertrophic cardiomyopathy which is expected to begin in Q4 2019. CK-274 is a novel selective cardiac myosin inhibitor, discovered by company scientists, in development for the potential treatment of hypertrophic cardiomyopathy (HCM).

Hypertrophic Cardiomyopathy (HCM) Therapeutics Market Higher Growth Prospects during | Key Players are S. A. , Pfizer, is inherited. Hypertrophic affects the muscular wall Cytokinetics Announces Data heart making them stiff. This thickening makes harder the heart to pump out the heart around the body. breath, chest pain, number Hypertrophic Cardiomyopathy (HCM) other associated may develop as HCM, including heart owing to increasing prevalence hypertrophic worldwide.

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